Preventing Disease with Nutrition

Preventative Pet Nutrition = Ideal Weight  & Evidence based supplements …but which products ….and in which breeds?

As a practicing wellness veterinarian for over 25 years no area has been as exciting (or challenging!) as treating and preventing disease with nutrition. Now that breed specific nutrition has been introduced it just got (more) interesting!

The following data has been compiled from the following lectures given by board certified veterinarians (all un-affiliated with pet food companies).  I have provided links directly to peer reviewed websites  so you can do your own research in this very exciting area.

As  veterinarians based in science we owe you the best science based perspectives to help you make the right decisions regarding nutritional products, amounts to feed and breed specific wellness issues  specific to your breed (or mixture of breeds!).

Important Disclaimer:

ALL OF THIS INFORMATION NEEDS TO BE CROSS CHECKED AND USED WITH THE ASSISTANCE & GUIDANCE OF YOUR VETERINARIAN

Without their guidance with regard to lab testing , a good physical exam, an accurate body condition score and knowing all underlying conditions (and for rescues/mixed breeds their true genetic makeup) much of this information cannot be properly or safely applied.

Most common diseases that we see as wellness veterinarians

  • 75 to 85%  have Periodontal Disease
  • 50 to 60% are above their Ideal Weight
  • 20 to 30% have Osteoarthritis
  • 10% to 20% have Allergies (inhalant or food)
  • 10% to 20%  Organ Failure (Kidney, Liver, Pancreatitis, Diabetes)
  • 5 to 10% have Urinary Stones (kidney or bladder)

Many of these are breed specific i.e. small breeds get much more periodontitis and larger breeds generally have much more arthritis & orthopedic problems like Cranial Cruciate Ligament disease and hip dysplasia (many small  breeds of course can have orthopedic disease such as patellar luxations and even hip dysplasia)

List of diseases we commonly treat with Rx foods & supplements (partial list)

  • Diabetes
  • Obesity (over 20% of ideal weight)
  • Periodontitis
  • Renal failure
  • Inhalant allergies
  • Food allergies
  • Liver disease
  • Pancreatitis

1) To prevent  Periodontitis ( affects 75 to 85% of pets over age 2)

Best resource for products:   Veterinary Oral Health Council  vohc.org

Best assurance of quality:  VOHC seal of approval given if food is at least 20% better than typical commercial brand in preventing.  Plaque claim is better than just a tartar claim

Specialists viewpoints Dr Fraser Hale DVM FAVD Dip AVDC

Dr Jan Bellows DVM FAVD Dip AVDC

Products

Rx Foods Hills T/D ® & Oral Care ® (VOHC accepted plaque & tartar claim) &  Purina DH ®  (plaque & tartar for cats, tartar only for dogs)  Iams Dental Defense ® (VOHC tartar claim one product in family)

Rawhide chews Purina rawhide chews®  have VOHC  acceptance, CET Hextras are not VOHC listed but are similar product with added evidence based ingredients

Water additive healthymouth.com 1st VOHC seal for a water additive (dog product) cat product is identical in formulation so should work as well in theory

Brushing using tooth pastes is the gold standard of dental homecare, a plaque retardant gel (Oravet®)  and a periodontal vaccine are outside the scope of this nutritional discussion but are the mainstays of prevention and should be discussed with your veterinarian.  more information

Breeds we specifically need to watch

All dogs under 20#, all Brachycephalics (bulldogs, pugs, etc) because of teeth crowding and thin bone around teeth that is rapidly destroyed by bacteria. Greyhounds have a genetic predisposition towards periodontitis.

Best one to one resource: a dentistry oriented veterinarian- ideally an American Veterinary Dental Society Member (AVDS) or a board certified veterinary dentist (We have 3 at U of Wisconsin!)

2)  To treat & prevent Obesity (20% over Ideal Weight)  affects 40 to 50% of pets

Best website: Association for Pet Obesity Prevention

Best resource for why &  how:  your veterinarian or westsidefamilypet.com

Products

Prescription  Foods:  Hills, Royal Canin, Purina, Iams  (all available  from your veterinarian)   Rx because  physical exam, lab testing, underlying cause screening and calorie counting need to be performed to be safe and effectively used when over 20% of ideal weight.  more info

“Over the counter” OTC foods:  “light formulas” (must be under 320 Calories/cup) many see Dr Wards website Can be used when less than 20% overweight or to prevent. Recent paper showed range of 240 to over 450 Cal/cup in so called “weight management” foods

Supplements: L-Carnitine, Isoflavones, EPA/DHA (fish oils), Level 2 evidence exists   more info

Breeds we specifically need to watch Beagles, Pugs, Scotties, Dalmatians, Cockers, Labs & Golden Retrievers

3) To treat & prevent Osteoarthritis (includes degenerative disease related to hip dysplasia, elbow dysplasia, CCL tears) 20 to 30% of pets affected

Best way to prevent JAVMA wt loss study

Best resource for supplements Consumerlab.com

Products

Rx Foods:  Purina JM ®  & Hills J/D ®  (force plate studies have been done by each company) just peer review published for J/D JAVMA reference Feline J/D just released!

Over the counter (OTC) Foods Feed only enough to maintain Ideal Weight

EPA/DHA Fish oils Anti-inflammatory dose of EPA  is 20mg per lb per day  (details)

Joint supplements (DASUquin ® & Glycoflex III ®) per label (details)

Challenges:  Not FDA controlled so there are major quality control & effectiveness issues

Breeds we specifically need to watch Labs, Golden Retrievers  & all large breeds, Cavalier King Charles, Boston Terriers, Yorkies, cats over the age of 10! (over 60% have arthritis)

4) To help treat Allergies (inhalant & food)  10 to 20%

Nonspecific treatment only  (inhalant blood testing  & food elimination trials must be done to diagnose)

EPA/DHA 20mg EPA/lb   about 7 to 8 human fish oil capsules for a Labrador

Challenges: dosing & convenience/compliance

Best resource for general info (human & some pet info) consumerlab.com

5)  Probiotics (emerging area)

Proviable ®   by Nutramax first to have published evidence see more

Purina Nutriflora ®, Vetriscience Everyday ®  & Iams Prostora ® all have good compettive products.

Quality control a huge issue (colony forming units etc) Look for at least 5 billion CFU’s. Properly handled & stored, use by __/___/___ dating   Current debates are concern is whether single strain or multiple strain is better. Stay tuned!

6) Breed specific nutrition

Royal Canin has established some very interesting information with regard to breed specific nutrition. Although there is certainly not data for all breeds and it needs to be researched much more they have provided some excellent and comprehensive background.  See their Yorkshire Terrier example 

Iams is doing some similar things

Stay tuned as we sift through for good solid science!

Other useful websites for additional information:

Ohio State College of Vet Med website “Comparing Prescription Diets”

www.vet.osu.edu

Your thoughts welcomed! Lets begin the dialogue.

Drs  Ken, Sarah , Katie & Dawn

References

Recent lectures by board certified DVM’s  (Nutrition, Internal Medicine & Surgeons) that I have attended to compile this review.

Naturally Neutraceutical Dr Rob Silver DVM  Madison WI Sept 2006
Using Nutrition to Enhance Patient Care   Dr Lisa Freeman DVM  DACVN Oct 2007
Hills Symposium of Evidence Based Nutrition  Dr Phil Roudebush DVM DACVIM  Nov 2007
UW Orthopedic Considerations for the Canine Athlete Dr Paul Manley DVM DACVS  Nov 2007
Rehabilitation in Veterinary Medicine Sherman Canapp DVM DACVS  et al April 2008
International Veterinary Rehabilitation Symposium Dr Julie Churchill DVM DACVIM Aug 2008
Practical Small Animal Nutrition Dr Kathyrn Michels DVM MS DACVN Lake Delton Feb 2009

EPA/DHA Fish oils resources

Freeman, Lisa OSU Waltham 2002 Nutritional Conference

Mueller RS, et al. J Sm An Proc 2004, 45:293-297.

Simopoulos AP. J Amer Coll Nutr 2002, 21:495-505

Bauer JE. I Am Vet Med Assoc 2006, 229:680-684.

Caterson B, et al. Hills European Symposium Genoa, Italy, Apr 2005:14-18.

Brown SA, et al. J Nutr 1998, 128:2765S-2767S.

Smith CE, et al. J Vet Inter Med 2007, 21:265-273.

Obesity resources

1. “Feeding for Fitness” Dr Julie Churchill DVM DACVIM PhD Intl Rehabilitation Symposium Aug 13 2008.

2. “Obesity’s missing link: The union of metabolism, genome & disease” Dr Jane Armstrong DVM MS MBA DACVIM U of Minn

3. “An evidence-based review of the use of therapeutic foods, owner education, exercise, and drugs for the management of obese and overweight pets” Dr Phillip Roudebush DVM, DACVIM et al JAVMA Vol 233 No 5 Sept 1, 2008

4. “An evidence-based review of the use of nutraceutical and dietary supplementation for the management of obese and overweight pets” Phillip Roudebush DVM, DACVIM et al JAVMA Vol 232 No 11 June 1, 2008

5. Effect of weight reduction on clinical signs of lameness in dogs with hip osteoarthritis Mark A  Tetrick, Peter Muir Journal of the American Veterinary Medical Association Apr 2000, Vol. 216, No. 7, Pages 1089-1091: 1089-1091.

Misc resources

Isoflavones Research Report Purina Research Report Volume 12 Issue 1

Obesity’s Missing Link: The union of metabolism, genome and disease Hills